Corneal Collagen Cross-Linking (CXL)
in Los Angeles​

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At CCRS, patients with weak cornea can undergo this strengthening procedure to prevent vision loss. The FDA approved CXL in 2016 to treat conditions such as keratectasia, a weakened cornea following LASIK, and keratoconus, a naturally occurring unstable cornea.

During CXL, the cornea is illuminated with UV light after Riboflavin (Vitamin B) is applied. This process creates cross-linking bridges between the corneal fibers and strengthens the tissue. CXL can be done instead of corneal transplantation for a fraction of the cost at CCRS.


Bladeless Wavefront

Small Incision Lenticule
Extraction (SMILE)

Implantable Collamer
Lens (ICL)

Refractive Cataract

Refractive Lens
Exchange (RLE)


Keratectomy (PRK)

Corneal Collagen
Cross-Linking (CXL)


View all FAQ
Corneal collagen cross-linking is a procedure done to strengthen a weakened cornea. Keratoconus is a genetic condition in which a cornea undergoes progressive weakening causing a deterioration in vision. In corneal collagen cross-linking, the adjacent corneal fibrils are cross-linked to make the cornea more rigid and sturdy. This process has shown to slow down or prevent further weakening of the cornea.
Corneal cross-linking is a two-step process. The first step is the removal of the epithelium, the surface layer of the cornea. The second step is treatment with UV light while applying Riboflavin (Vitamin B). The entire process takes about two hours.
In the FDA study, corneal cross-linking has shown to be effective in preventing further weakening of the cornea. In our experience, some people have experienced significant improvement in their vision following the procedure.
Yes, you are awake during the procedure. We numb your eye throughout the procedure with drops, so there is no pain. You can bring an earphone to listen to your favorite music.
Recovery from corneal cross-linking can take one to two weeks. Your vision will be blurry to varying degrees and will clear as you heal. Some people choose to do one eye at a time.
There is no pain during the procedure as your eye is kept numb. However, after your procedure, for the first few days, you may experience discomfort. We will give you numbing drops and pain-relieving pills to help you during your recovery.